New Covid Vaccine Approved by the FDA to Target Highly Contagious Strains

By: David Donovan | Published: Aug 22, 2024

The new Covid vaccine is expected to be approved as soon as Thursday by the Food and Drug Administration (FDA).

Since the first series, the vaccines have been updated three times to match the current strains. The shots are expected to be available within days once approved by the FDA.

Earlier Rollout

Since the majority of the United States is still afflicted by the summer wave of Covid illness, the timing of the new vaccines is crucial—the rollout occurred in mid-September last year. 

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CDC's Roybal campus in Atlanta, Georgia. The building is glass-fronted and has a brick wall in front of it lined with trees. The sign is blue and has the outline of a bird on it.

Source: James Gathany/Centers for Disease Control and Prevention

The Centers for Disease Control and Prevention reported on Monday that the number of people who test positive for Covid continues to rise and that the number of people who visit the emergency room for Covid has been rising since the middle of May. Hospitalizations are on the rise as well.

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Updated Formulas

The new shots from Pfizer and Moderna are intended to focus on the KP.2 strain, a relative of the exceptionally infectious JN.1 variation that started circulating rapidly in the U.S. the previous winter. The drugmakers working on the new doses in June after the FDA encouraged them to renew the formulas to match the form of the infection that was making progress in the U.S.

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Entrance to former Pfizer World Headquarters building (1961-2023), there is a sign above the door, there are people walking in front of the building and a tree out front.

Source: ajay_suresh/Flickr

A third vaccine, from drugmaker Novavax, has been refreshed to focus on the JN.1 strain. JN.1 and KP.2 have generally faded from dissemination, as indicated by the CDC.

New Sister Strain

As of Saturday, a sister strain known as KP.3.1.1 accounts for 36% of all new Covid cases, and another sister strain known as KP.3 accounts for approximately 17%.

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Masks with an exhalation valve. The valves are a weak point that can transmit the viruses outwards. There are two masks showing the inside and outside as well as a box for them.

Source: Зеледеев/Wikimedia Commons

It’s unclear precisely how powerful the antibodies will be against the more up-to-date strains, yet specialists expect that they will safeguard against serious disease.

“Substantially Improved”

According to a Pfizer spokesperson who spoke to NBC News, the company’s vaccine produces an immune response that is “substantially improved” when compared to earlier versions of the vaccine against multiple variants that are currently in circulation, including KP.3.

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NewYork-Presbyterian/Weill Cornell Medical Center, 68th street facade, there are trees outside of the building lined with shrubbery.

Source: Kenneth C. Zirkel/Wikimedia Commons

There are “very minor sequence differences” between the variations, according to John Moore, a professor of microbiology and immunology at Weill Cornell Medical College.

Incremental Changes

KP.3.1.1 is similar to JN.1 and KP.2, according to a paper that was published this month in the journal Infectious Diseases. However, it has a few more mutations that may make it easier to spread.

Weill Cornell Medical Center (left) and the Hospital for Special Surgery (right), 2006. Water is visible in front of the buildings and is tree lined.

Source: WorldIslandInfo.com/Flickr

Moore stated, “All these changes are incremental. They do not change the overall big picture. KP.3.1.1 is just another step in the road that the overall Omicron lineage is taking towards greater transmissibility.”

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“Last a Very Long Time”

In a prior interview, Dr. Ashish Jha, dean of the Brown University School of Public Health and a previous White House Coronavirus response coordinator, said Coronavirus is possibly endemic in the U.S., meaning that it is following “a relatively predictable pattern that will last a very long time.”

Ashish Jha speaking in the James S. Brady Press Briefing Room of the White House on April 26, 2022. He is at a podium as people are seated listening to him and a camera films him.

Source: The White House/Flickr

This indicates that, like annual flu shots, we will receive an updated Covid vaccine each year to safeguard against mutations and waning immunity.

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CDC Recommendations

According to CDC data as of May 11, only 22.5% of adults had received the updated Covid vaccine from the previous year. Only 14.4% of children between the ages of 6 months and 17 years old were vaccinated.

Tom Harkin Global Communications Center of the CDC. The sign is blue and has the outline of a bird on it. There is green space in front of the glass building.

Source: James Gathany/Centers for Disease Control and Prevention

The CDC recommended that all Americans over the age of six months receive the new vaccines for this fall.

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“Vaccines Are Still Helpful”

However, infectious disease specialist at the University of Toronto Dr. Isaac Bogoch stated that it is difficult to make a one-size-fits-all recommendation regarding who ought to get the vaccine, particularly for young adults who are in good health.

The Donnelly Centre is part of the Discovery District in Toronto University, there is a statue in front of the glass building as well as trees.

Source: Ryan Tir/Flickr

He declared, “It’s fair to say that the vaccines are still helpful, certainly on an individual level, and to some extent on a community level.”

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Recommended Cohorts

It’s fundamentally critical that individuals at the most severe risk of an extreme Coronavirus infection — including individuals older than 65, or with debilitated immune systems or underlying medical issues, like heart disease or obesity— get the vaccine, Bogoch said.

Dr. Isaac Bogoch posing in a hallway wearing a doctors coat, shirt, tie and stethoscope. There is text for an “Ask Me Anything” session on Reddit and the logo for UHN imposed on top.

Source: UHN/X

He stated, “The heavy lifting of the vaccine is really in protecting the most vulnerable people from severe outcomes, like hospitalization and death.”

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Immune Boost

Covid has affected millions of Americans in recent weeks and months. A benefit of the mid-year wave is that individuals who have recently recuperated have an immune boost to ward off future diseases.

CDC Building 17 in Atlanta, Georgia, as seen from Emory University, is is sunset and there are towers coming out of the industrial looking building with a mixture of steel and brick.

Source: Nrbelex/nl.en.wikipedia

Since the vaccines will be accessible earlier compared to last year, the topic of timing for the most benefit through the winter is more pressing. As indicated by CDC advice, if you’ve contracted Covid recently, you may consider delaying your vaccine dose by 3 months.” 

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Protection from Infection

Experts recommend getting the vaccine as soon as it becomes available for people who are at high risk of serious illness. According to Dr. Ofer Levy, the director of the Precision Vaccines Program at Boston Children’s Hospital, this is due to the possibility that vaccination provides greater protection than infection does.

Dr. Ofer Levy with two women in a lecture hall with a view of a screen above them as they take a selfie.

Source: levy_o/X

The severity of an infection, the strain, a person’s age, and their health all play a role in how well protected they are from infection.

According to Yale School of Medicine immunology professor Akiko Iwasaki, getting the vaccine so close to recovery from infection may not be as beneficial for healthy young people.

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